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AttributesValues
rdf:type
rdfs:label
  • Core-Binding Factor
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Core-Binding Factor
UMLS_CUI
  • C0212320
Legacy_Concept_Name
  • Core-Binding_Factor
FULL_SYN
  • CBFSYNCI
  • Core-Binding FactorPTNCI
DEFINITION
  • CBF is an alpha/beta heterodimeric transcription factor involved in the transcriptional regulation of several genes important in hematopoiesis. The CBFalpha subunit binds directly to the enhancer core DNA sequence on target genes, whereas the beta subunit does not bind the DNA directly but increases the affinity and stabilizes the binding of the alpha subunit to the DNA.NCI
code
  • C17683
is someValuesFrom of
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