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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Chaparrin
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Chaparrin
NSC_Code
  • 132794
  • 79404
UMLS_CUI
  • C0630780
CAS_Registry
  • 4616-50-6
Legacy_Concept_Name
  • Chaparrin
FULL_SYN
  • ChaparrinSYDTPNSC0079404
  • ChaparrinPTNCI
DEFINITION
  • A quassinoid phytochemical isolated from Simaba cedron and other plant species with potential antineoplastic activity. Chaparrin is a mixture of compounds that includes flavonoids, antioxidants, and nordihydroguaiaretic acid (NDGA). NDGA is an antioxidant and lipoxygenase inhibitor that promotes cell differentiation, induces G1 phase cell-cycle arrest, and causes apoptosis in certain cancer cell lines. (NCI04)NCI
code
  • C1767
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