About: Apoptosis

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Apoptosis
rdfs:subClassOf	Cell Death Process nodeID://b646435 nodeID://b646436 nodeID://b646437
Semantic_Type	Phenomenon or Process
Preferred_Name	Apoptosis
UMLS_CUI	C0162638
ALT_DEFINITION	A type of cell death in which a series of molecular steps in a cell leads to its death. This is the body's normal way of getting rid of unneeded or abnormal cells. The process of programmed cell death may be blocked in cancer cells.NCI-GLOSS
Legacy_Concept_Name	Apoptosis
FULL_SYN	PCDABNCI Apoptotic ProcessSYNCI programmed cell deathPTNCI-GLOSSCDR0000407582 ApoptosisPTNCI Programmed Cell DeathSYNCI apoptosisPTNCI-GLOSSCDR0000046524
DEFINITION	A form of programmed cell death that begins when a cell receives internal or external signals, then proceeds through a series of characteristic stages typically including rounding-up of the cell, retraction of pseudopods, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane blebbing, and ends with the death of the cell.NCI
DesignNote	Important in ontogenesis, tumorigenesis, tissue turnover, lymphocyte selection and function and hormone-induced atrophy.
code	C17557
is rdfs:subClassOf of	Anoikis Negative Regulation of Apoptosis Positive Regulation of Apoptosis Leukocyte Apoptotic Process Caspase-Dependent Apoptosis Caspase-Independent Apoptosis
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