About: Dopamine Receptor D2     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Dopamine Receptor D2
equivalentClass
OMIM_Number
  • 126450
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Receptor
Preferred_Name
  • Dopamine Receptor D2
UMLS_CUI
  • C0058698
Legacy_Concept_Name
  • Dopamine_Receptor-D2
FULL_SYN
  • DRD2SYNCI
  • DRD2 ReceptorSYNCI
  • Dopamine D2 ReceptorSYNCI
  • Dopamine Receptor D2PTNCI
Swiss_Prot
  • P14416
DEFINITION
  • Neurotransmission mediated by the Dopamine D2 Receptor (DRD2) plays a key role in the control of movement, in reward and reinforcement mechanisms in psychiatric disorders, and in the neuromodulation of appetitive behaviors. Acting through D2 dopamine receptors, dopamine specifically inhibits the vascular permeabilizing and angiogenic activities of VEGF by inducing endocytosis of VEGF receptor 2, preventing VEGF binding, receptor phosphorylation, and signaling.NCIfrom OMIM 126450 and NCI
code
  • C17292
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