About: Pentetic Acid Calcium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Pentetic Acid Calcium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Pentetic Acid Calcium
UMLS_CUI
  • C1518953
CAS_Registry
  • 2531-75-1
In_Clinical_Trial_For
  • Facilitate urinary excretion of Y90 in radioimmunotherapy of TAC-expressing malignancies
ALT_DEFINITION
  • A drug that protects healthy tissues from the toxic effects of anticancer drugs.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42562
PDQ_Closed_Trial_Search_ID
  • 42562
Legacy_Concept_Name
  • Pentetic_Acid_Calcium
FULL_SYN
  • Calcium DTPASYNCI
  • Calcium-DTPASYNCI
  • pentetic acid calciumPTNCI-GLOSSCDR0000045514
  • Ca-DTPAABNCI
  • Pentetic Acid CalciumPTNCI
  • Calcium Pentetic AcidSYNCI
DEFINITION
  • The calcium salt of pentetic acid, a synthetic chelating agent related to the chelating agent ethylenediaminetetraacetic acid (EDTA). Pentetic acid chelates with the metallic radioisotopic moieties of unbound, extracellular radioimmunotherapeutic agents, resulting in higher specific tumor cell binding of radioimmunotherapeutic agents; this results in improved tumor cell radiocytotoxicity and the sparing of normal cells and tissues from the radiocytotoxic effects of these agents.NCI
code
  • C1710
is Has_Salt_Form of
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