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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Transferrin Receptor
rdfs:subClassOf
Semantic_Type
  • Receptor
Preferred_Name
  • Transferrin Receptor
UMLS_CUI
  • C0034845
ALT_DEFINITION
  • Membrane glycoproteins found in high concentrations on iron-utilizing cells. They specifically bind iron-bearing transferrin, are endocytosed with its ligand and then returned to the cell surface where transferrin without its iron is released.MSH2001
  • major vehicle for cellular uptake of iron; receptor expression is tightly regulated by available iron, via an "iron-responsive element" (IRE) on its mRNA which prevents translation when occupied by an iron- sensitive binding protein.CSP2000
Legacy_Concept_Name
  • Transferrin_Receptor
FULL_SYN
  • Transferrin ReceptorPTNCI
DEFINITION
  • Homodimeric human Transferrin Receptors (M28B Peptidase Family) are type II membrane proteins involved in the cellular import of transferrin-bound iron and appear necessary for iron metabolism, cell function, and erythrocyte differentiation. (NCI)NCI
DesignNote
  • Protein_Plays_Role_In_Biological_Process: Iron Metabolism
code
  • C17079
is rdf:first of
is someValuesFrom of
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