About: Plasminogen Activator Inhibitor 1     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Plasminogen Activator Inhibitor 1
rdfs:subClassOf
OMIM_Number
  • 173360
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Plasminogen Activator Inhibitor 1
UMLS_CUI
  • C0030190
Legacy_Concept_Name
  • Plasminogen_Activator_Inhibitor-1
FULL_SYN
  • Plasminogen Activator Inhibitor 1PTNCI
  • Plasminogen Activator Inhibitor-1SYNCI
  • Endothelial Plasminogen Activator InhibitorSYNCI
  • PAISYNCI
  • PAI1SYNCI
  • Serine or Cysteine Proteinase Inhibitor Clade E Member 1SYNCI
  • PAI-1ABNCI
  • NexinSYNCI
  • Plasminogen Activator Inhibitor Type 1SYNCI
  • PLANH1SYNCI
  • SERPINE1SYNCI
  • Serpin E1SYNCI
Swiss_Prot
  • P05121
DEFINITION
  • Plasminogen activator inhibitor 1 (402 aa, ~45 kDa) is encoded by the human SERPINE1 gene. This protein plays a role in both cell adhesion and the modulation of plasmin activity.NCI
DesignNote
  • Plasminogen Activator Inhibitor-1 is a member of the serpin superfamily that inhibits both tissue-type and urokinase-type plasminogen activators. PAI1 shows structural similarities to angiotensinogen, alpha-1-antitrypsin, and antithrombin III and also regulates motility through the interaction of vitronectin with its receptor, integrin alpha-V-beta-3. (from OMIM 173360)
code
  • C16947
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