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AttributesValues
rdf:type
rdfs:label
  • Mixed Lymphocyte Reaction Test
rdfs:subClassOf
Semantic_Type
  • Laboratory Procedure
Preferred_Name
  • Mixed Lymphocyte Reaction Test
UMLS_CUI
  • C0023509
ALT_DEFINITION
  • Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.MSH2001
Legacy_Concept_Name
  • Mixed_Lymphocyte_Reaction_Test
FULL_SYN
  • Mixed Lymphocyte CultureSYNCI
  • Mixed Lymphocyte Reaction TestPTNCI
  • Mixed T Cells, B CellsSYNCI
DEFINITION
  • Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (usually measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with mitomycin C or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.NCI
code
  • C16790
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