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AttributesValues
rdf:type
rdfs:label
  • Temoporfin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Temoporfin
PubMedID_Primary_Reference
  • 17516041
UMLS_CUI
  • C0379149
CAS_Registry
  • 122341-38-2
FDA_UNII_Code
  • FU21S769PF
Contributing_Source
  • FDA
ALT_DEFINITION
  • An anticancer drug that is also used in cancer prevention. It belongs to the family of drugs called photosensitizing agents.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42851
PDQ_Closed_Trial_Search_ID
  • 42851
Chemical_Formula
  • C44H32N4O4
Legacy_Concept_Name
  • Temoporfin
CHEBI_ID
  • CHEBI:9437
FULL_SYN
  • temoporfinPTNCI-GLOSSCDR0000045564
  • mTHPCABNCI
  • FoscanFBNCI
  • m-Tetrahydroxyphenyl-chlorinSYNCI
  • TEMOPORFINPTFDAFU21S769PF
  • 5,10,15,20-Tetra-(m-hydroxyphenyl)chlorinSNNCI
  • meta-TetrahydroxyphenylchlorinSNNCI
  • meta-Tetrahydroxyphenyl ChlorinSNNCI
  • TemoporfinPTNCI
DEFINITION
  • A synthetic light-activated chlorin with photodynamic activity. Upon systemic administration, temoporfin distributes throughout the body and is taken up by tumor cells. Upon stimulation of temoporfin by non-thermal laser light (at 652 nm), and in the presence of oxygen, this agent produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to tumor cells. This may kill tumor cells and may reduce the tumor size.NCI
code
  • C1669
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