About: HMG-CoA Reductase Inhibitor     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • HMG-CoA Reductase Inhibitor
rdfs:subClassOf
Semantic_Type
  • Chemical Viewed Functionally
Preferred_Name
  • HMG-CoA Reductase Inhibitor
UMLS_CUI
  • C0360714
ALT_DEFINITION
  • Any of a group of drugs that lower the amount of cholesterol and certain fats in the blood. Statins inhibit a key enzyme that helps make cholesterol. Statin drugs are being studied in the prevention and treatment of cancer.NCI-GLOSS
  • Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.MSH2002_06_01
Legacy_Concept_Name
  • HMG-CoA_Reductase_Inhibitor
CHEBI_ID
  • CHEBI:35664
FULL_SYN
  • Hydroxymethylglutaryl CoenzymeA Reductase InhibitorsSYNCI
  • HMG-CoA reductase inhibitorPTNCI-GLOSSCDR0000430880
  • HMG-CoA Reductase InhibitorPTNCI
  • statinPTNCI-GLOSSCDR0000390255
  • StatinSYNCI
  • hydroxymethylglutaryl-coenzyme A reductase inhibitorPTNCI-GLOSSCDR0000430881
DEFINITION
  • Any substance that inhibits HMG-CoA reductase, a key enzyme in cholesterol synthesis. Inhibition of HMG-CoA reductase acts to lower plasma cholesterol and lipoprotein levels.NCI
code
  • C1655
is rdfs:subClassOf of
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