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AttributesValues
rdf:type
rdfs:label
  • Motexafin Lutetium
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Motexafin Lutetium
NSC_Code
  • 695239
UMLS_CUI
  • C0338310
CAS_Registry
  • 156436-90-7
  • 246252-04-0
FDA_UNII_Code
  • 0A85BJ22L6
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is being studied in the treatment of cancer using photodynamic therapy. It belongs to the family of drugs called metallotexaphyrins.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42402
PDQ_Closed_Trial_Search_ID
  • 42402
Chemical_Formula
  • C48H66N5O10.2C2H3O2.Lu.H2O
Legacy_Concept_Name
  • Motexafin_Lutetium
FULL_SYN
  • Lutetium texaphyrinSYDTPNSC0695239
  • LutexSYDTPNSC0009704
  • motexafin lutetiumPTNCI-GLOSSCDR0000390301
  • Lu texSYDTPNSC0695239
  • lutetium texaphyrinPTNCI-GLOSSCDR0000045469
  • LutexBRNCI
  • Lu-TexABNCI
  • AntrinBRNCI
  • OptrinBRNCI
  • LutrinBRNCI
  • Motexafin LutetiumPTNCI
  • Lutetium TexaphrinSYNCI
  • PCI-0123CNNCI
  • MOTEXAFIN LUTETIUMPTFDA0A85BJ22L6
  • Lutetium TexaphyrinSYNCI
DEFINITION
  • A pentadentate aromatic metallotexaphyrin with photosensitizing properties. Motexafin lutetium preferentially accumulates in tumor cells due to their increased rates of metabolism and absorbs light, forming an extended high energy conformational state that produces high quantum yields of singlet oxygen, resulting in local cytotoxic effects. (NCI04)NCI
code
  • C1651
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