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AttributesValues
rdf:type
rdfs:label
  • DNA Damage
rdfs:subClassOf
Semantic_Type
  • Cell or Molecular Dysfunction
Preferred_Name
  • DNA Damage
UMLS_CUI
  • C0012860
Legacy_Concept_Name
  • DNA_Damage
FULL_SYN
  • DNA DamagePTNCI
DEFINITION
  • Drug-, radiation-induced, or spontaneous injuries to DNA that introduce deviations from its normal double-helical conformation. These changes include structural distortions that interfere with replication and transcription, as well as point mutations that disrupt base pairs and exert damaging effects on future generations through changes in DNA sequence. If the damage is minor, it can often be repaired (DNA repair); extensive damage can induce apoptosis.NCI
code
  • C16507
is rdfs:subClassOf of
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