About: Adenylate Cyclase     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Adenylate Cyclase
equivalentClass
OMIM_Number
  • 603302
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Enzyme
Preferred_Name
  • Adenylate Cyclase
UMLS_CUI
  • C0001492
Legacy_Concept_Name
  • Adenylate_Cyclase
FULL_SYN
  • ATP Pyrophosphate-LyaseSYNCI
  • Adenyl Cyclase 9SYNCI
  • ADCY9SYNCI
  • Adenylate CyclasePTNCI
  • Adenylylcyclase 9SYNCI
  • Adenylyl Cyclase 9SYNCI
  • EC 4.6.1.1SYNCI
Swiss_Prot
  • O60503
DEFINITION
  • Adenylyl cyclases are membrane-associated enzymes of the lyase class that are expressed in most human tissues. These enzymes catalyze the formation of cyclic AMP and pyrophosphate from ATP and are regulated by a family of G protein-coupled receptors, protein kinases, and calcium. Adenylyl cyclase is encoded by the ADCY9 gene and widely distributed. It is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. It may play a fundamental role in situations where fine interplay between intracellular Ca(2+) and cAMP determines the cellular function. It also may be a physiologically relevant docking site for calcineurin.NCI
code
  • C16264
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