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AttributesValues
rdf:type
rdfs:label
  • Etalocib
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Etalocib
UMLS_CUI
  • C0298619
CAS_Registry
  • 161172-51-6
In_Clinical_Trial_For
  • Non-small cell lung cancer; pancreatic cancer
FDA_UNII_Code
  • THY6RIW44R
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called leukotriene B4 receptor antagonists.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38111
PDQ_Closed_Trial_Search_ID
  • 38111
Chemical_Formula
  • C33H33FO6
Legacy_Concept_Name
  • LY293111
FULL_SYN
  • 2-[2-Propyl-3-[3-[2-ethyl-4-(4-fluorophenyl)-5-hydroxyphenoxy]propoxy]phenoxy]benzoic AcidSNNCI
  • ETALOCIBPTFDATHY6RIW44R
  • 2-[3-[3-[(5-Ethyl-4'-fluoro-2-hydroxy[1,1'-biphenyl]-4-yl)oxy]propoxy]-2-propylphenoxy]benzoic AcidSNNCI
  • LY293111PTNCI-GLOSSCDR0000044981
  • LY293111CNNCI
  • EtalocibPTNCI
  • 2-[3-[3-[(5-Ethyl-4'-fluoro-2-hydroxy[1,1'-biphenyl]-4-yl)oxy]propoxy]-2-propylphenoxy]benzoic AcidPTDCP50603
DEFINITION
  • A second-generation selective leukotriene B4 receptor (LTB4R) antagonist with potential antineoplastic activity. Although the exact underlying mechanism through which LY293111 exerts its effects has not been fully elucidated, this agent selectively binds to and blocks LTB4Rs, thereby inhibiting the downstream signalling pathway. LY29311 has been shown to induce apoptosis and inhibits cellular proliferation in LTB4R expressing cells, such as pancreatic cancer cells.NCI
code
  • C1626
is someValuesFrom of
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