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AttributesValues
rdf:type
rdfs:label
  • Pyrazoloacridine
equivalentClass
Has_Target
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Pyrazoloacridine
NSC_Code
  • 366140
UMLS_CUI
  • C0280970
In_Clinical_Trial_For
  • Glioblastoma multiforme; neuroblastoma
ALT_DEFINITION
  • A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called acridines.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 41418
PDQ_Closed_Trial_Search_ID
  • 41418
Legacy_Concept_Name
  • Pyrazoloacridine
FULL_SYN
  • PyrazoloacridinePTNCI
  • pyrazoloacridinePTNCI-GLOSSCDR0000045366
DEFINITION
  • A 9-methoxy acridine compound containing a reducible 5-nitro substituent. Pyrazoloacridine appears to intercalate into DNA and inhibit RNA synthesis, DNA synthesis, and the activities of topoisomerases I and II, thereby causing cytotoxicity. (NCI04)NCI
code
  • C1564
is someValuesFrom of
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