About: Rhenium Re-186 Hydroxyethylidene Diphosphonate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Rhenium Re-186 Hydroxyethylidene Diphosphonate
rdfs:subClassOf
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Rhenium Re-186 Hydroxyethylidene Diphosphonate
UMLS_CUI
  • C0280809
CAS_Registry
  • 140709-07-5
PDQ_Open_Trial_Search_ID
  • 41205
PDQ_Closed_Trial_Search_ID
  • 41205
Legacy_Concept_Name
  • Re_186_Hydroxyethylidene_Diphosphonate
FULL_SYN
  • Re-186 HEDPABNCI
  • Rhenium Re 186 EtidronateSYNCI
  • Rhenium Re-186 Hydroxyethylidene DiphosphonatePTNCI
  • Rhenium-186 HEDPSYNCI
  • 186Re-EtidronateSYNCI
  • Re 186 Hydroxyethylidene DiphosphonateSYNCI
  • Re-186 Hydroxyethylidene DiphosphonateSYNCI
DEFINITION
  • An synthetic compound containing the organic phosphonate hydroxyethylidene diphosphonate (HEDP) labeled with the radioisotope rhenium Re 186. Re-186 hydroxyethylidene diphosphonate binds to hydroxyapatite in bone, delivering a cytotoxic dose of beta radiation to primary and metastatic bone tumors. Re-186 is a beta emitter with a short half-life, a radioisotope profile that provides localized antitumor radiocytotoxicity while sparing extramedullary bone marrow tissues.NCI
code
  • C1562
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