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AttributesValues
rdf:type
rdfs:label
  • Phenyl Acetate
equivalentClass
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Phenyl Acetate
NSC_Code
  • 27795
UMLS_CUI
  • C0220893
CAS_Registry
  • 122-79-2
Accepted_Therapeutic_Use_For
  • Adjunctive therapy for the prevention and treatment of hyperammonemia in the chronic management of patients with urea cycle enzymopathy
FDA_UNII_Code
  • 355G9R500Y
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug being studied in the treatment of cancer.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 41664
PDQ_Closed_Trial_Search_ID
  • 41664
Chemical_Formula
  • C8H8O2
Legacy_Concept_Name
  • Phenyl_Acetate
CHEBI_ID
  • CHEBI:8082
FULL_SYN
  • AcetylphenolSYDTPNSC0027795
  • AcetylphenolSYNCI
  • Acetic Acid Phenyl EsterSYNCI
  • PHENYL ACETATEPTFDA355G9R500Y
  • Phenyl AcetatePTNCI
  • Phenyl AcetateSYNCI
  • Phenyl acetateSYDTPNSC0027795
  • phenylacetatePTNCI-GLOSSCDR0000045383
DEFINITION
  • An aromatic fatty acid metabolite of phenylalanine with potential antineoplastic activity. Naturally occurring in mammals, phenylacetate induces differentiation, growth inhibition, and apoptosis in tumor cells. Implicated mechanisms of action include decreased protein prenylation, activation of the peroxisome proliferation-activated receptors, inhibition of DNA methylation, and depletion of glutamine. (NCI04)NCI
code
  • C1501
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