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AttributesValues
rdf:type
rdfs:label
  • Lodenosine
equivalentClass
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Lodenosine
NSC_Code
  • 613792
UMLS_CUI
  • C0220150
CAS_Registry
  • 110143-05-0
  • 110143-10-7
FDA_UNII_Code
  • 3WB2LGT4R1
Contributing_Source
  • FDA
Chemical_Formula
  • C10H12FN5O2
Legacy_Concept_Name
  • _2_Fluoro-2_3_Dideoxyadenosine
FULL_SYN
  • 2'-F-dd-ara-ASYNCI
  • 2'-beta-fluoro-2',3'-dideoxyadenosineSNNCI
  • F-ddAABNCI
  • 2'-FddASNNCI
  • DRG-0246CNNCI
  • 9-(2,3-Dideoxy-2-fluoro-beta-D-threo-pentofuranosyl) AdenineSNNCI
  • LodenosinePTNCI
  • 2'-F-dd-araAABNCI
  • 2'-Beta-Fluoro-2',3'-DideoxyadenosineSNNCI
  • 2'-FddAABNCI
  • LODENOSINEPTFDA3WB2LGT4R1
  • 9-(2,3-Dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-9H-purin-6-amineSNNCI
  • 2'-Fluoro-2',3'-DideoxyadenosineSYNCI
DEFINITION
  • A nucleoside reverse transcriptase inhibitor analog of adenosine. Lodenosine is a synthetic purine fluoro-dideoxyadenosine derivative that was rationally designed to have improved chemical and enzymatic stability. It has shown activity against clinical isolates and cell lines that are resistant to AZT, dideoxyinosine, and dideoxycytosine.NCI
code
  • C1499
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