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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Filgrastim
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Filgrastim
NSC_Code
  • 614629
UMLS_CUI
  • C0210630
CAS_Registry
  • 121181-53-1
Accepted_Therapeutic_Use_For
  • Aplastic neutropenia; Bone marrow transplantation; Cancer patients receiving myelosuppressive chemotherapy; Congenital neutropenia; Idiopathic or cyclic neutropenia; Peripheral blood progenitor cell mobilization
FDA_UNII_Code
  • PVI5M0M1GW
Contributing_Source
  • FDA
ALT_DEFINITION
  • A colony-stimulating factor that stimulates the production of neutrophils (a type of white blood cell). It is a cytokine that is a type of hematopoietic (blood-forming) agent.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 41057
PDQ_Closed_Trial_Search_ID
  • 41057
Legacy_Concept_Name
  • Filgrastim
FULL_SYN
  • TevagrastimBRNCI
  • filgrastimPTNCI-GLOSSCDR0000045332
  • r-metHuG-CSFABNCI
  • Tbo-filgrastimSYNCI
  • Filgrastim XM02SYNCI
  • G-CSFABNCI
  • Recombinant Methionyl Human Granulocyte Colony Stimulating FactorSYNCI
  • rG-CSFSYNCI
  • FILGRASTIMPTFDAPVI5M0M1GW
  • NeupogenBRNCI
  • FilgrastimPTNCI
DEFINITION
  • A recombinant, non-glycosylated cytokine which is chemically identical to or similar to the endogenous cytokine human granulocyte colony-stimulating factor (G-CSF) isoform B, with immunomodulating activity. Filgrastim binds to and activates G-CSF receptors with the same biological activity and stability as the endogenous cytokine, thereby controlling the production, differentiation, and function of neutrophilic granulocyte progenitors.NCI
code
  • C1474
is someValuesFrom of
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