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AttributesValues
rdf:type
rdfs:label
  • BN, Rat Strain
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Mammal
Preferred_Name
  • BN, Rat Strain
UMLS_CUI
  • C0034700
Contributing_Source
  • CDISC
ALT_DEFINITION
  • The common rat, Rattus norvegicus.CDISC
Legacy_Concept_Name
  • BN_Rat_Strain
FULL_SYN
  • BROWN NORWAYPTCDISC
  • BN, Rat StrainPTNCI
  • Brown Norway RatSYNCI
DEFINITION
  • Originally from China and now ubiquitous, Rattus norvegicus is the founder strain for many strains of rat used in biomedical research today. The brown rat has a coarse brown or black coat with a pale underside, and a long nearly hairless tail. Tumors of epithelium 28% in males, 2% in females. Ureter tumors 20% in females, 6% in males. Most common neoplastic lesions in males were urinary bladder carcinoma 35%, pancreas islet adenoma 15%, pituitary adenoma 14%, lymphoreticular sarcoma 14%, adrenal cortex adenoma 12%, medullary thyroid carcinoma 9%, adrenal pheochromocytoma 8%. Four other types of tumors were observed. In females: pituitary adenoma 26%, ureter carcinoma 22%, adrenal cortical adenoma 19%, cervix sarcoma 15%, mammary gland fibroadenoma 11%, islet adenoma 11%. Twelve other tumor types were observed (Burek and Hollander 1975a).NCI
code
  • C14395
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