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AttributesValues
rdf:type
rdfs:label
  • WF, Rat Strain
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Mammal
Preferred_Name
  • WF, Rat Strain
UMLS_CUI
  • C0034707
Contributing_Source
  • CDISC
ALT_DEFINITION
  • A Wistar substrain derived by Furth (1945), this inbred rat strain is a white albino with pink eyes, genotype c. The Wistar Furth rat carries a heteropyenotic Y chromosome that is used as a cellular marker.CDISC
  • A Wistar substrain derived by Furth (1945), this inbred rat strain is a white albino with pink eyes, genotype c. The Wistar Furth rat carries a heteropyenotic Y chromosome that is used as a cellular marker. Leukemia develops in 15-22% of these rats, which is characterized by mononuclear cells with reddish granules. The Wistar Furth rat exhibits good reproductive performance and is docile, with an averages life span of 22 months.NCI
Legacy_Concept_Name
  • WF_Rat_Strain
FULL_SYN
  • WISTAR FURTHPTCDISC
  • WF, Rat StrainPTNCI
  • Wistar Furth RatSYNCI
DEFINITION
  • In females tumors include 27% pituitary, 21% mammary, 3% adrenal, 9% leukemia (generalized), 7% lymphoma (malignant), 3% lipomas and 4% unclassified (Kim et al 1960). Mean life span 21 months in females and 23 months in males. Leukemia 15-22% characterised by an unusual type of mononuclear cell containing reddish granules. Incidence of spontaneous pituitary tumors 38% in rats older than 10 months of age, increasing to a maximum of 69% at 28-32 months of age. Higher incidence in females (71%) than in males (35%)NCI
code
  • C14390
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