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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Endogenous Retrovirus
rdfs:subClassOf
Semantic_Type
  • Virus
Preferred_Name
  • Endogenous Retrovirus
UMLS_CUI
  • C0600466
Legacy_Concept_Name
  • Endogenous_Retrovirus
FULL_SYN
  • ERVABNCI
  • Endogenous RetrovirusPTNCI
DEFINITION
  • Genetic elements propagated primarily through the germline, with a proviral structure, i.e. the chromosomally-integrated form of retroviruses and regulated by cellular processes. Could be involved in development and serve as progenitors to pathogenic retroviruses. Classified as ecotropic or xenotropic. Ecotropic viruses can be transmitted to cells of the same species and can produce malignancies. Xenotropic viruses cannot infect cells from their host species but are infectious in heterologous species. Cycles of transcription and reverse transcription make the elements mobile and mutagenic.NCI
code
  • C14334
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