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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Imiquimod
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Imiquimod
NSC_Code
  • 369100
  • 741062
UMLS_CUI
  • C0718327
CAS_Registry
  • 99011-02-6
Accepted_Therapeutic_Use_For
  • Condyloma; Superficial Basal Cell Carcinoma; Actinic Keratosis
In_Clinical_Trial_For
  • Basal cell carcinoma
FDA_UNII_Code
  • P1QW714R7M
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat early basal cell skin cancer and certain other skin conditions. It is being studied in the treatment of other types of cancer. Imiquimod is a type of biological response modifier.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 38558
PDQ_Closed_Trial_Search_ID
  • 38558
Chemical_Formula
  • C14H16N4
Legacy_Concept_Name
  • Imiquimod
CHEBI_ID
  • CHEBI:36704
FULL_SYN
  • ImiquimodPTDCP50541
  • 1H-Imidazo(4,5-c)quinolin-4-amine, 1-(2-methylpropyl)-SNNCI
  • 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinolineSNNCI
  • AldaraPTNCI-GLOSSCDR0000507517
  • R 837CNNCI
  • IMIQUIMODPTFDAP1QW714R7M
  • AldaraBRNCI
  • S 26308CNNCI
  • ZyclaraBRNCI
  • ImiquimodPTNCI
  • imiquimodPTNCI-GLOSSCDR0000045080
DEFINITION
  • A synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. (NCI04)NCI
code
  • C1431
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