About: RXY/FXpSXP Motif     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • RXY/FXpSXP Motif
rdfs:subClassOf
Semantic_Type
  • Amino Acid Sequence
Preferred_Name
  • RXY/FXpSXP Motif
UMLS_CUI
  • C1514675
Legacy_Concept_Name
  • RXY_FXpSXP_Motif
FULL_SYN
  • RXY/FXpSXP MotifPTNCI
  • RXY/FXpSXP DomainSYNCI
DEFINITION
  • The 14-3-3 family of proteins mediates signal transduction by binding to phosphoserine-containing proteins. RXY/FXpSXP Motif is one of two different binding motifs that are present in nearly all known 14-3-3 binding proteins. The14-3-3 dimer binds tightly to single molecules containing tandem repeats of phosphoserine motifs, implicating bidentate association as a signaling mechanism with molecules such as Raf, BAD, and Cbl. (from OMIM)NCI
code
  • C13976
is someValuesFrom of
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