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AttributesValues
rdf:type
rdfs:label
  • SAM Domain
rdfs:subClassOf
Semantic_Type
  • Amino Acid Sequence
Preferred_Name
  • SAM Domain
UMLS_CUI
  • C1519124
Legacy_Concept_Name
  • SAM_Domain
FULL_SYN
  • Sterile Alpha MotifSYNCI
  • Sterile Alpha DomainSYNCI
  • SAM MotifSYNCI
  • SAM DomainPTNCI
DEFINITION
  • The approximately 70 amino acid SAM (Sterile Alpha Motif) domain has been identified in over 400 different proteins with diverse cellular function, from yeast to man. SAM domains have been implicated in mediating protein-protein interaction via the formation of homo and hetero-typic oligomers. The residues at the interface of the EphA4 and EphB2 SAM domain homodimers have been mapped, but the factors that determine specificity remain to be determined. (Pawson Lab, SLRI, Mount Sinai Hospital, 2003)NCI
code
  • C13960
is someValuesFrom of
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