About: Hematoporphyrin Derivative     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Hematoporphyrin Derivative
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Hematoporphyrin Derivative
NSC_Code
  • 265328
UMLS_CUI
  • C0121300
CAS_Registry
  • 68335-15-9
ALT_DEFINITION
  • A drug used in photodynamic therapy that is absorbed by tumor cells. When exposed to light, it becomes active and kills the cancer cells.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 40859
PDQ_Closed_Trial_Search_ID
  • 40859
Legacy_Concept_Name
  • Hematoporphyrin_Derivative
FULL_SYN
  • Hematoporphyrin derivativeSYDTPNSC0603062
  • HPDABNCI
  • Hematoporphyrin DerivativePTNCI
  • hematoporphyrin derivativePTNCI-GLOSSCDR0000045322
  • PhotofrinBRNCI
  • photofrinSYNCI-GLOSSCDR0000046105
DEFINITION
  • A complex mixture of monomeric and aggregated porphyrins with photosensitizing activity. Upon systemic administration, hematoporphyrin derivatives accumulate in tumor cells and, once activated by red laser light (630 nm), in the presence of oxygen, produce singlet oxygen and other reactive oxygen radicals, resulting in local radical-mediated tumor cell death.NCI
code
  • C1377
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software