About: Pamidronate Disodium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Pamidronate Disodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Pamidronate Disodium
NSC_Code
  • 720699
UMLS_CUI
  • C0356588
CAS_Registry
  • 109552-15-0
Accepted_Therapeutic_Use_For
  • Hypercalcemia of malignancy; Osteolytic bone lesions of multiple myeloma; Osteolytic bone metastases of breast cancer; Pagets disease
In_Clinical_Trial_For
  • Multiple myeloma; Osteogenesis imperfecta
FDA_UNII_Code
  • 8742T8ZQZA
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39149
PDQ_Closed_Trial_Search_ID
  • 39149
Chemical_Formula
  • C3H9NO7P2.2Na.5H2O
Legacy_Concept_Name
  • Pamidronate_Disodium
FULL_SYN
  • PAMIDRONATE DISODIUMPTFDA8742T8ZQZA
  • ArediaBRNCI
  • AminomuxFBNCI
  • Pamidronate DisodiumPTNCI
  • GCP-23339ACNNCI
DEFINITION
  • The disodium salt of the synthetic bisphosphonate pamidronate. Although its mechanism of action is not completely understood, pamidronate appears to adsorb to calcium phosphate crystals in bone, blocking their dissolution by inhibiting osteoclast-mediated bone resorption. This agent does not inhibit bone mineralization and formation.NCI
code
  • C1345
is someValuesFrom of
is Has_Salt_Form of
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