About: Recombinant Interleukin 10     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Recombinant Interleukin 10
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Recombinant Interleukin 10
UMLS_CUI
  • C1522550
CAS_Registry
  • 130068-27-8
PDQ_Open_Trial_Search_ID
  • 43226
PDQ_Closed_Trial_Search_ID
  • 43226
Legacy_Concept_Name
  • Therapeutic_Interleukin_10
FULL_SYN
  • Cytokine Synthesis Inhibitory FactorSYNCI
  • CSIFABNCI
  • IL-10ABNCI
  • B cell-derived T cell growth factorSYNCI
  • Interleukin-10SYNCI
  • Recombinant Interleukin 10PTNCI
DEFINITION
  • A recombinant cytokine chemically identical to or similar to interleukin-10 (IL-10) secreted by certain leukocytes with immunomodulatory activities. IL-10 is an anti-inflammatory cytokine, capable of inhibiting synthesis of pro-inflammatory cytokines, such as Interferon-gamma, IL-2, IL-3, TNF-alpha, and GM-CSF. However, it also has stimulatory effects on certain T cells, mast cells, and B cells, as well as inducing expression of class II major histocompatibility complex.NCI
code
  • C1320
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