About: Recombinant Pleiotrophin     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Recombinant Pleiotrophin
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Recombinant Pleiotrophin
UMLS_CUI
  • C1524097
CAS_Registry
  • 134034-50-7
Legacy_Concept_Name
  • Recombinant_Pleiotrophin
FULL_SYN
  • PleiotrophinSYNCI
  • Recombinant PleiotrophinPTNCI
  • Heparin-Binding Neurotrophic FactorSYNCI
  • HBNFABNCI
  • HARPABNCI
  • OSF-1ABNCI
  • Recombinant Heparin-Binding Neurotrophic FactorSYNCI
  • Osteoblast Specific Factor 1SYNCI
  • HBGF-8ABNCI
  • Heparin-Binding Growth Factor-8SYNCI
  • Heparin Affin Regulatory PeptideSYNCI
DEFINITION
  • A recombinant form of the heparin-binding cytokine pleiotrophin. Developmentally regulated, pleiotrophin functions as a growth factor during embryogenesis and the neonatal period, contributing to trophoblast formation, organ development, bone formation, and early brain development by inducing the differentiation and proliferation of neuronal tissue. Expressed in certain tumor cell types, this agent may stimulate tumor cell growth, angiogenesis, and metastasis. (NCI04)NCI
code
  • C1307
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