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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Vinepidine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Vinepidine
UMLS_CUI
  • C0078255
CAS_Registry
  • 68170-69-4
FDA_UNII_Code
  • W3375J6V0Y
Contributing_Source
  • FDA
Chemical_Formula
  • C46H56N4O9
Legacy_Concept_Name
  • Vinepidine
FULL_SYN
  • 4'-DeoxyepivincristineSYNCI
  • VINEPIDINEPTFDAW3375J6V0Y
  • VinepidinePTNCI
DEFINITION
  • A vinca alkaloid compound and semi-synthetic vincristine derivative with antineoplastic activity. Vinepidine binds to and stabilizes tubulin, thereby preventing tubulin polymerization and depolymerization, which result in microtubule assembly and disassembly, respectively. Treated cells are unable to complete mitosis process and are arrested in the metaphase, thereby leading to an inhibition of cell growth.NCI
code
  • C1274
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