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AttributesValues
rdf:type
rdfs:label
  • Thymalfasin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Thymalfasin
UMLS_CUI
  • C0076612
CAS_Registry
  • 62304-98-7
FDA_UNII_Code
  • W0B22ISQ1C
Contributing_Source
  • FDA
Chemical_Formula
  • C129H215N33O55
Legacy_Concept_Name
  • Thymalfasin
FULL_SYN
  • ThymalfasinPTNCI
  • Thymosin Alpha 1SYNCI
  • ZadaxinBRNCI
  • THYMALFASINPTFDAW0B22ISQ1C
  • Thymosin Alpha 1PTDCP09090
DEFINITION
  • A synthetic analogue of thymosin-alpha-1, a 28-amino acid protein derived from the precursor protein prothymosin-alpha. Exhibiting a variety of immunoregulating properties, thymosin-alpha-1 induces differentiation of murine T-cell precursors and human thymocytes and the terminal differentiation of functionally immature cord blood lymphocytes and induces production of IL-2, high affinity IL-2 receptors, and B-cell growth factors by peripheral blood mononuclear cells. T-helper and cytotoxic/suppressor T-cell populations are targets of thymosin activity. Thymosin-alpha-1 has been shown to increase the efficiency of antigen presentation by macrophages and to be an endogenous modulator of alpha-thrombin activity. (NCI04)NCI
code
  • C1253
is someValuesFrom of
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