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AttributesValues
rdf:type
rdfs:label
  • Shiga Toxin
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Hazardous or Poisonous Substance
Preferred_Name
  • Shiga Toxin
UMLS_CUI
  • C0074447
CAS_Registry
  • 75757-64-1
ALT_DEFINITION
  • A toxin produced by SHIGELLA DYSENTERIAE. It is the protype of class of toxins that inhibit protein synthesis by blocking the interaction of ribosomal RNA; (RNA, RIBOSOMAL) with PEPTIDE ELONGATION FACTORS.MSH2002_06_01
Legacy_Concept_Name
  • Shiga_Toxin
FULL_SYN
  • Shiga ToxinPTNCI
DEFINITION
  • A bacterial toxin produced by Shigella dysenteriae and by some strains of E. coli that inhibits protein synthesis by blocking the interaction of ribosomal RNA with peptide elongation factors. The non-catalytic beta subunit of Shiga toxin may be useful as a fusion vector for induction of antigen-specific cytotoxic T lymphocyte responses.NCI
code
  • C1225
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