About: Recombinant Prothymosin Alpha     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Recombinant Prothymosin Alpha
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Recombinant Prothymosin Alpha
UMLS_CUI
  • C1527078
Legacy_Concept_Name
  • Therapeutic_Prothymosin_Alpha
FULL_SYN
  • Prothymosin AlphaSYNCI
  • Recombinant Prothymosin AlphaPTNCI
DEFINITION
  • A recombinant form of the endogenous polypeptide hormone that exerts immunomodulatory effects primarily on mononuclear cells. Prothymosin alpha stimulates the production of various cytokines including granulocyte/macrophage colony stimulating factor (GM-CSF) alpha, gamma interferon (IFN) and interleukins such as IL-2. This agent may also increase some tumor antigens expression, thus inducing better T lymphocyte responses to tumor cells. Combined with chemotherapy, prothymosin alpha may exhibit significant anti-tumor effects. This agent also helps to regenerate lymph node and bone marrow cells after treatment with certain toxic chemotherapeutics. (NCI04)NCI
code
  • C1203
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