About: Eniluracil / 5-FU Combination Tablet     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Eniluracil / 5-FU Combination Tablet
rdfs:subClassOf
Has_Target
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Eniluracil / 5-FU Combination Tablet
NSC_Code
  • 710026
UMLS_CUI
  • C0393027
PDQ_Open_Trial_Search_ID
  • 42618
PDQ_Closed_Trial_Search_ID
  • 42618
Legacy_Concept_Name
  • Ethynyluracil_Fluorouracil
FULL_SYN
  • Eniluracil / 5-FU Combination TabletPTNCI
  • Ethynyluracil/FluorouracilSYNCI
  • GW776/5-FluorouracilSYNCI
  • GW776/5-FUSYNCI
  • 776C85/5-FUSYNCI
DEFINITION
  • A combination tablet of ethynyluracil and fluorouracil. Fluorouracil is an antimetabolite fluoropyrimidine analog of the nucleoside pyrimidine with antineoplastic activity. Ethynyluracil is an orally-active fluoropyrimidine analog that inhibits dihydropyrimidine dehydrogenase, the rate-limiting enzyme that catabolizes and inactivates 5-fluorouracil in the liver. This may lead to an increase in the bioavailability and, effectiveness of fluorouracil.NCI
code
  • C11252
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