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AttributesValues
rdf:type
rdfs:label
  • FOLFOX Regimen
rdfs:subClassOf
Semantic_Type
  • Therapeutic or Preventive Procedure
Preferred_Name
  • FOLFOX Regimen
UMLS_CUI
  • C0915342
ALT_DEFINITION
  • An abbreviation for a chemotherapy combination used to treat colorectal cancer that is advanced or has come back. It is also being studied in the treatment of other types of cancer. It includes the drugs leucovorin calcium (folinic acid), fluorouracil, and oxaliplatin. FOLFOX-4, FOLFOX-6, modified FOLFOX-6 (mFOLFOX-6), and FOLFOX-7 are different in the doses of the three drugs and the ways they are given.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 42512
PDQ_Closed_Trial_Search_ID
  • 42512
Legacy_Concept_Name
  • Fluorouracil_Leucovorin-Calcium_Oxaliplatin
FULL_SYN
  • Fluorouracil/Leucovorin Calcium/OxaliplatinSYNCI
  • CF/5-FU/L-OHPSYNCI
  • FOLFOX RegimenPTNCI
  • FOLFOXPTNCI-GLOSSCDR0000346521
  • FOLFOX regimenPTNCI-GLOSSCDR0000635816
DEFINITION
  • One of several chemotherapy regimens that include leucovorin calcium (calcium folinate), 5-fluorouracil and oxaliplatin and which may be used in the treatment of advanced-stage and metastatic colorectal cancer. FOLFOX regimens differ in agent dosing and administration schedule and include FOLFOX 4, FOLFOX 6, modified FOLFOX 6 (mFOLFOX 6) and FOLFOX 7.NCI
DesignNote
  • FDA approved as first line treatment of Advanced Colorectal Cancer
code
  • C11197
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