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AttributesValues
rdf:type
rdfs:label
  • Cefixime
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Cefixime
UMLS_CUI
  • C0060400
CAS_Registry
  • 79350-37-1
FDA_UNII_Code
  • 97I1C92E55
Contributing_Source
  • FDA
ALT_DEFINITION
  • An antibiotic drug used to treat infection. It belongs to the family of drugs called cephalosporins.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 37809
PDQ_Closed_Trial_Search_ID
  • 37809
Chemical_Formula
  • C16H15N5O7S2.3H2O
Legacy_Concept_Name
  • Cefixime
CHEBI_ID
  • CHEBI:472657
FULL_SYN
  • CEFIXIMEPTFDA97I1C92E55
  • FK 027CNNCI
  • SupraxBRNCI
  • cefiximePTNCI-GLOSSCDR0000386199
  • CefiximePTNCI
DEFINITION
  • A broad-spectrum, third-generation cephalosporin antibiotic derived semisynthetically from the marine fungus Cephalosporium acremonium with antibacterial activity. As does penicillin, the beta-lactam antibiotic cefixime inhibits bacterial cell wall synthesis by disrupting peptidoglycan synthesis, resulting in a reduction in bacterial cell wall stability and bacterial cell lysis. Stable in the presence of a variety of beta-lactamases, this agent is more active against gram-negative bacteria and less active against gram-positive bacteria compared to second-generation cephalosporins.NCI
code
  • C1100
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