About: Fluorine F 18-labeled S-(3-Fluoropropyl)homocysteine Hydrochloride

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About: Fluorine F 18-labeled S-(3-Fluoropropyl)homocysteine Hydrochloride Goto Sponge NotDistinct Permalink

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Attributes	Values
rdf:type	Class
rdfs:label	Fluorine F 18-labeled S-(3-Fluoropropyl)homocysteine Hydrochloride
rdfs:subClassOf	Radioconjugate
Semantic_Type	Pharmacologic Substance Indicator, Reagent, or Diagnostic Aid
Preferred_Name	Fluorine F 18-labeled S-(3-Fluoropropyl)homocysteine Hydrochloride
PDQ_Open_Trial_Search_ID	744815
PDQ_Closed_Trial_Search_ID	744815
FULL_SYN	([(18)F]FPHCysSYNCI Fluorine F 18-labeled S-(3-Fluoropropyl)homocysteine HydrochloridePTNCI 18F-FPMABNCI
DEFINITION	The hydrochloride salt form of a radioconjugate composed of a synthetic derivative of the amino acid methionine radiolabeled with fluoride F 18, with potential use as a tumor imaging agent during positron emission tomography (PET). Upon administration, fluorine F 18-labeled S-(3-fluoropropyl) homocysteine is preferentially taken up by tumor cells through an amino acid transporter, which is overexpressed by cancer cells. As tumor cells have a higher rate of proliferation than normal cells, these cancer cells have increased rates of protein synthesis and thus an increased demand for amino acids. This allows for visualization of tumors cells upon PET.NCI
code	C104269

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