About: Injectable Astragalus membranaceus Polysaccharide     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Injectable Astragalus membranaceus Polysaccharide
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Injectable Astragalus membranaceus Polysaccharide
NCI_META_CUI
  • CL438305
PDQ_Open_Trial_Search_ID
  • 742587
PDQ_Closed_Trial_Search_ID
  • 742587
FULL_SYN
  • Injectable PG2SYNCI
  • Injectable APSSYNCI
  • Injectable Astragalus membranaceus PolysaccharidePTNCI
DEFINITION
  • An injectable form of a polysaccharide isolated from the radix of Astragalus membranaceus (PG2), used in traditional Chinese medicine, with potential hematopoiesis inducing and immunomodulating activities. Upon injection, APS may be able to relieve certain chemotherapy-induced side effects, including myelosuppression, fatigue, mucositis, pain, nausea and vomiting, as well as loss of appetite and body weight. Also, APS may exert immunostimulatory activities by stimulating B-lymphocytes, activating T-lymphocytes, inducing cytokine production, and activating macrophages and natural killer cells through as of yet unidentified mechanism(s). APS may improve compliance of radiotherapy and/or chemotherapy.NCI
code
  • C103822
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