About: Ginsenoside Rg3 Capsule     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Ginsenoside Rg3 Capsule
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ginsenoside Rg3 Capsule
NCI_META_CUI
  • CL438137
PDQ_Open_Trial_Search_ID
  • 742493
PDQ_Closed_Trial_Search_ID
  • 742493
FULL_SYN
  • Ginsenoside Rg3 CapsulePTNCI
  • Shen Yi CapsuleSYNCI
DEFINITION
  • A capsule containing the steroidal saponin ginsenoside Rg3 isolated from the root of Panax ginseng, with potential cancer preventive and anti-angiogenic activities. Upon oral administration, ginsenoside Rg3 appears to inhibit endothelial cell proliferation, migration and tubular formation, and promotes cancer cell apoptosis. This agent also modulates the activities of certain growth factors, such as vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and matrix metalloproteinases (MMPs), on tumor angiogenesis. In addition, ginsenoside Rg3 may be able to sensitize cancer cells to some chemotherapeutic agents.NCI
code
  • C103300
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