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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Beta-elemene
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Beta-elemene
UMLS_CUI
  • C1101268
PDQ_Open_Trial_Search_ID
  • 740161
PDQ_Closed_Trial_Search_ID
  • 740161
FULL_SYN
  • Beta-elemenePTNCI
  • 1alpha,2beta,4beta)-1-Methyl-2,4-bis(methylvinyl)-1- vinylcyclohexaneSNNCI
DEFINITION
  • One of the isomers of elemene, a lipid soluble sesquiterpene and the active component isolated from the Chinese medicinal herb Rhizoma zedoariae with potential antineoplastic and chemopreventive activities. Although the exact mechanism of action through which beta-elemene exerts its effect has yet to be fully elucidated, this agent appears to induce apoptosis through different mechanisms of action and induces cell cycle arrest at different stages based on the tumor cell type involved. Beta-elemene may sensitize cancer cells to other chemotherapeutic agents.NCI
code
  • C103177
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