About: Iodine I 131 Rituximab     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Iodine I 131 Rituximab
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Iodine I 131 Rituximab
NCI_META_CUI
  • CL437218
ALT_DEFINITION
  • A radioactive substance being studied in the treatment of liver cancer. It is a form of poppy seed oil that contains iodine, some of which is the radioactive substance iodine I 131. It builds up in the blood and lymph vessels in the liver and may kill cancer cells. It is a type of radiopharmaceutical.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 739942
PDQ_Closed_Trial_Search_ID
  • 739942
FULL_SYN
  • Iodine I 131 RituximabPTNCI
  • 131I-RituxanSYNCI
  • (131)I-RituximabSYNCI
DEFINITION
  • A radioimmunoconjugate comprised of rituximab, a recombinant chimeric monoclonal antibody directed against the CD20 antigen, and labeled with iodine I 131 with potential antineoplastic activity. The antibody moiety of iodine I 131 rituximab binds to the CD20 antigen thereby delivering cytotoxic iodine I 131 specifically to cancer cells expressing CD20. The CD20 antigen, a hydrophobic transmembrane protein, is expressed on normal pre-B and mature B lymphocytes.NCI
code
  • C102981
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