About: Aspirin/Simvastatin/Atenolol/Ramipril/Thiazide Capsule     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Aspirin/Simvastatin/Atenolol/Ramipril/Thiazide Capsule
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Aspirin/Simvastatin/Atenolol/Ramipril/Thiazide Capsule
NCI_META_CUI
  • CL437147
PDQ_Open_Trial_Search_ID
  • 737711
PDQ_Closed_Trial_Search_ID
  • 737711
FULL_SYN
  • Aspirin/Simvastatin/Atenolol/Ramipril/Thiazide CapsulePTNCI
  • PolycapSYNCI
  • QuintapillFBNCI
DEFINITION
  • An orally bioavailable combination pill containing aspirin, simvastatin, atenolol, ramipril and thiazide with preventive activity against cardiovascular disease (CVD). Aspirin is a cyclooxygenase inhibitor with antiplatelet, analgesic, antipyretic and anti-inflammatory activities; simvastatin is a statin with a cholesterol lowering effect; and the beta-blocker atenolol as well as the ACE inhibitor ramipril and the thiazide diuretic all have blood pressure lowering activity. Upon oral administration of aspirin/simvastatin/atenolol/ramipril/thiazide capsule, the combined effects of the active ingredients in this formulation lower the risk of CVD.NCI
code
  • C102868
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