About: Ulimorelin Hyrdrochloride     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Ulimorelin Hyrdrochloride
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ulimorelin Hyrdrochloride
UMLS_CUI
  • C2353772
CAS_Registry
  • 951326-02-6
PDQ_Open_Trial_Search_ID
  • 735985
PDQ_Closed_Trial_Search_ID
  • 735985
FULL_SYN
  • Ulimorelin HyrdrochloridePTNCI
  • TZP-101CNNCI
DEFINITION
  • The hydrochloride salt form of ulimorelin, a macrocyclic ghrelin peptidomimetic, with potential gastrointestinal (GI) prokinetic activity. Upon intravenous administration, ulimorelin binds to the ghrelin receptor in the GI tract and may stimulate GI motility. Ghrelin is a natural ligand for growth hormone secretagogue receptors and is normally localized in the proximal GI tract. The ghrelin receptor signaling pathway mediates multiple GI functions, including motility and gastric emptying.NCI
code
  • C102755
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