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AttributesValues
rdf:type
rdfs:label
  • Bruceantin
rdfs:subClassOf
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Bruceantin
NSC_Code
  • 165563
UMLS_CUI
  • C0054160
CAS_Registry
  • 41451-75-6
PDQ_Open_Trial_Search_ID
  • 39169
PDQ_Closed_Trial_Search_ID
  • 39169
Legacy_Concept_Name
  • Bruceantin
FULL_SYN
  • BruceantinPTDCP50082
  • Picras-3-en-21-oic acid, 15-[(3, 4-dimethyl-1-oxo-2-pentenyl)oxy]-13,20-epoxy-3,11,12-trihydroxy-2, 16-dioxo-, methyl ester, [11.beta.,12.alpha.,15.beta.(E)]-SYDTPNSC0165563
  • Picras-3-en-21-oic Acid, 15-[(3,4-dimethyl-1-oxo-2-pentenyl)oxy]-13,20-epoxy-3,11, 12-trihydroxy-2,16-dioxo-, Methyl Ester, (11.beta.,12.alpha,15.beta.(E))SNNCI
  • 2H-3, 11c-(Epoxymethano)phenanthro[10,1-bc]pyran, Picras-3-en-21-oic Acid DerivativeSNNCI
  • BRUCEANTINSYDTPNSC0165563
  • [11Beta,12alpha,15beta(E)]-15-[(3,4-dimethyl-1-oxo-2-pentenyl)oxy]-13,20-epoxy-3,11,12-trihydroxy-2,16-dioxopicras-3-en-21-oic Acid Methyl EsterSNNCI
  • Picras-3-en-21-oic acid, 15-[(3, 4-dimethyl-1-oxo-2-pentenyl)oxy]-13,20-epoxy-3,11,12-trihydroxy-2, 16-dioxo-, methyl ester [11.beta.,12.alpha.,15.beta.(E]-SYDTPNSC0165563
  • BruceantinPTNCI
DEFINITION
  • A triterpene quassinoid antineoplastic antibiotic isolated from the plant Brucea antidysenterica. Bruceantin inhibits the peptidyl transferase elongation reaction, resulting in decreased protein and DNA synthesis. Bruceantin also has antiamoebic and antimalarial activity. (NCI04)NCI
code
  • C1025
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