About: Iobenguane I-124     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Iobenguane I-124
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Iobenguane I-124
NCI_META_CUI
  • CL435900
PDQ_Open_Trial_Search_ID
  • 732715
PDQ_Closed_Trial_Search_ID
  • 732715
FULL_SYN
  • Iodine I 124 IobenguaneSYNCI
  • Iodine I 124 MetaiodobenzylguanidineSYNCI
  • Iobenguane I-124PTNCI
  • 124I-metaiodobenzylguanidineSYNCI
  • 124I-MIBGABNCI
DEFINITION
  • A radioconjugate composed of the positron-emitting radioisotope iodine I 124 labeled to iobenguane, the synthetic aralkylguanidine analogue of the neurotransmitter norepinephrine (NE), with potential diagnostic imaging applications upon positron emitting tomography (PET) or computed tomography (CT). Upon administration, iobenguane I-124 is taken up and accumulates in the granules of adrenal medullary chromaffin cells and in the pre-synaptic granules of adrenergic neurons in a manner almost identical with that of NE. In turn, tumor cells can be imaged upon PET or CT.NCI
code
  • C101776
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