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AttributesValues
rdf:type
rdfs:label
  • Verteporfin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Biologically Active Substance
Preferred_Name
  • Verteporfin
UMLS_CUI
  • C0387288
CAS_Registry
  • 129497-78-5
Accepted_Therapeutic_Use_For
  • Photosensitizer, subfoveal choroidal neovascularization
In_Clinical_Trial_For
  • Photosensitizer in refractory brain tumors
FDA_UNII_Code
  • 0X9PA28K43
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 42130
PDQ_Closed_Trial_Search_ID
  • 42130
Legacy_Concept_Name
  • Verteporfin
CHEBI_ID
  • CHEBI:32293
FULL_SYN
  • VerteporfinPTNCI
  • BPD-MAABNCI
  • VisudyneBRNCI
  • VERTEPORFINPTFDA0X9PA28K43
  • Benzoporphyrin Derivative Monoacid Ring ASYNCI
DEFINITION
  • A synthetic light-activated agent with photodynamic activity. Upon systemic administration, verteporfin accumulates in neovessels in the eye and, once stimulated by nonthermal red light in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to neovascular endothelium and blood vessel occlusion. (NCI04)NCI
code
  • C1014
is someValuesFrom of
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