About: CBFB/MYH11 Fusion Protein     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • CBFB/MYH11 Fusion Protein
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • CBFB/MYH11 Fusion Protein
UMLS_CUI
  • C0381246
FULL_SYN
  • CBFB/MYH11 Fusion ProteinPTNCI
  • CBFb-MYH11 Fusion ProteinSYNCI
  • CBFbeta-MYH11 Fusion ProteinSYNCI
  • Core-Binding Factor Subunit Beta/Myosin-11 Fusion ProteinSYNCI
  • CBFbeta-SMMHC Fusion ProteinSYNCI
  • CBFbeta/SMMHC Fusion ProteinSYNCI
DEFINITION
  • A fusion protein encoded by the CBFB/MYH11 fusion gene. This protein is comprised of most of the core-binding factor subunit beta fused to the C-terminal dimerization domain of myosin-11.NCI
DesignNote
  • The CBFB/MYH11 fusion protein appears to act as a dominant-negative for the transcriptional activation activity mediated by the intact core-binding factor subunit beta protein.
code
  • C101052
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