About: CARS/ALK Fusion Protein     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • CARS/ALK Fusion Protein
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • CARS/ALK Fusion Protein
NCI_META_CUI
  • CL433575
FULL_SYN
  • CARS-ALK Fusion ProteinSYNCI
  • CARS/ALK Fusion ProteinPTNCI
  • Cysteinyl-tRNA Synthetase, Cytoplasmic/ALK Tyrosine Kinase Receptor Fusion ProteinSYNCI
DEFINITION
  • A fusion protein (680 aa, ~75 kDa) that is encoded by the CARS/ALK fusion gene. This protein contains 606 amino acids from the N-terminus of the cysteinyl-tRNA synthetase, cytoplasmic protein and the cytoplasmic domain of the ALK tyrosine kinase receptor protein.NCI
DesignNote
  • The CARS/ALK fusion protein is a constitutively dimerized and activated tyrosine kinase.
code
  • C99872
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