About: Telomere Maintenance Gene     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Telomere Maintenance Gene
rdfs:subClassOf
Semantic_Type
  • Gene or Genome
Preferred_Name
  • Telomere Maintenance Gene
UMLS_CUI
  • C1336700
Legacy_Concept_Name
  • Telomere_Maintenance_Gene
FULL_SYN
  • Telomere Maintenance GenePTNCI
DEFINITION
  • Telomere Maintenance Genes encode specialized proteins bound to telomeric DNA repeats and directly involved in maintaining/protecting chromosome telomere ends to prevent a damage response that halts cell proliferation. Telomerase, which lengthens telomeric DNA by RNA-templated addition of repeated DNA sequences, is regulated by proteins that bind to the telomeric DNA repeats and to additional proteins to assemble a higher-order telomeric complex. (NCI)NCI
code
  • C20338
is rdfs:subClassOf of
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