About: Bisacodyl     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/drugbank/Drug, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type
http://linked.open...gbank/description
  • Bisacodyl is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of constipation and for the management of neurogenic bowel dysfunction as well as part of bowel preparation before medical examinations, such as for a colonoscopy. (en)
http://linked.open...y/drugbank/dosage
http://linked.open...generalReferences
  • # Stiens SA, Luttrel W, Binard JE: Polyethylene glycol versus vegetable oil based bisacodyl suppositories to initiate side-lying bowel care: a clinical trial in persons with spinal cord injury. Spinal Cord. 1998 Nov;36(11):777-81. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/9848486 # Robert Engelhorn, Ernst Seeger and Jan H. Zwaving "Laxatives" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2000. # Wexner SD, Beck DE, Baron TH, Fanelli RD, Hyman N, Shen B, Wasco KE: A consensus document on bowel preparation before colonoscopy: prepared by a task force from the American Society of Colon and Rectal Surgeons (ASCRS), the American Society for Gastrointestinal Endoscopy (ASGE), and the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). Gastrointest Endosc. 2006 Jun;63(7):894-909. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/16733101 # Kudo K, Miyazaki C, Kadoya R, Imamura T, Jitsufuchi N, Ikeda N: Laxative poisoning: toxicological analysis of bisacodyl and its metabolite in urine, serum, and stool. J Anal Toxicol. 1998 Jul-Aug;22(4):274-8. "Pubmed":http://www.ncbi.nlm.nih.gov/pubmed/9681329 (en)
http://linked.open...gy/drugbank/group
  • approved (en)
http://linked.open...drugbank/halfLife
  • 16 hours (en)
http://linked.open...ugbank/indication
  • Indicated for cleansing of the colon as a preparation for colonoscopy in adults. (en)
sameAs
Title
  • Bisacodyl (en)
adms:identifier
http://linked.open...mechanismOfAction
  • Induces diarrhea which cleanses the colon. (en)
http://linked.open...y/drugbank/patent
http://linked.open.../drugbank/synonym
  • Bisacodyl (en)
  • Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester) (en)
  • Bisacodilo (en)
  • Bisacodyle (en)
  • Bisacodylum (en)
  • Dulcolax (en)
  • Spirolax (en)
http://linked.open...ynthesisReference
  • U.S. Patent 2,764,590. (en)
foaf:page
http://linked.open...ugbank/IUPAC-Name
http://linked.open...gy/drugbank/InChI
http://linked.open...Molecular-Formula
http://linked.open.../Molecular-Weight
http://linked.open...noisotopic-Weight
http://linked.open...y/drugbank/SMILES
http://linked.open.../Water-Solubility
http://linked.open...ogy/drugbank/logP
http://linked.open...ogy/drugbank/logS
http://linked.open...l/drug/hasATCCode
http://linked.open...nd-Acceptor-Count
http://linked.open...-Bond-Donor-Count
http://linked.open...drugbank/InChIKey
http://linked.open...urface-Area--PSA-
http://linked.open...nk/Polarizability
http://linked.open...bank/Refractivity
http://linked.open...atable-Bond-Count
http://linked.open...ugbank/absorption
  • 15% (en)
http://linked.open...casRegistryNumber
  • 603-50-9 (en)
http://linked.open...rugbank/clearance
  • primarily in the feces, systemically absorbed drug is excreted in the urine. (en)
http://linked.open...k/Bioavailability
http://linked.open...bank/Ghose-Filter
http://linked.open...nk/MDDR-Like-Rule
http://linked.open...ank/Melting-Point
http://linked.open...k/Number-of-Rings
http://linked.open...siological-Charge
http://linked.open...bank/Rule-of-Five
http://linked.open...tional-IUPAC-Name
http://linked.open...-strongest-basic-
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